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Izon Science Support Centre

qNano

qNano

Information and support for using the qNano TRPS measurement system.

qNano Technical Documentation

qNano User Manual

qNano Quick Start Guide

qNano Installation and Setup

I've just received my instrument. How do I get started?

How do I set up my qNano system?

What are the required computer specifications?

What additional pieces of lab equipment and/or consumables are required?

Overview: qNano Training Programme

How do I apply vacuum with the VPM?

How do I apply pressure with the VPM?

The holding stage doesn't move. What can I do?

Which way should I orientate the nanopore on the holding stage?

How do I install a Pressure Reading Module on the qNano?

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qNano Software

How can I get the latest Control Suite Software release for the qNano?

Unable to Connect the qNano to the Izon Control Suite?

Are Apple MAC or Linux operating systems currently supported?

How much free hard drive space is required for software installation?

I do not have permission to save onto the default Izon Data folder. How can I resolve this issue?

What file format can I export from the Izon Control Suite Software?

Why is the Classic Capture tile greyed out?

I accidentally closed down the software. How do I resume my measurements?

How do I get back to the Home screen menu?

The software doesn't respond during "Calibrate Nanopore Stretch"

Tips: Use of spacebar to navigate through Assistants

How do I process files recorded on Classic Capture mode?

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qNano Operation

What is the Nanopore Wetting Procedure for the qNano and why is it important?

Video: Maintaining a stable baseline current

Video: Sample Changeover

Components Overview: Variable Pressure Module (VPM)

How do I perform zeta potential measurements on the qNano?

What are the recommended qNano settings for zeta potential measurements compared with conventional size and concentration measurements?

When should the low gain stage be used?

How can I improve my signal-to-noise ratio?

How do I increase the particle rate?

What is Resolution Range?

What is the Green Zone?

What is Analysis Size Fraction (or Concentration Fraction)?

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qNano Care and Maintenance

When and how should I clean the lower fluid cell?

How do I disassemble and clean the fluid cell?

The centre of the lower fluid cell looks grey. Is that normal?

I'm working with virus particles. How do I decontaminate the instrument?

Is my VPM functioning correctly?

The stretcher unit doesn't move when the stretch adjustment handle is rotated.

How often should the instrument be serviced?

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qNano Troubleshooting

The rate plot does not display a constant gradient. Why is this important and what can be done to rectify the issue?

There is no change in pressure as I move the plunger. Is the VPM leaking?

Is my Pressure Reading Module (PM2) working?

Baseline current keeps railing when working with larger nanopores (NP1000 and larger)

The baseline current is fluctuating/drifting. How do I stabilise the baseline current?

I have followed the system setup steps but the baseline current is still ~0 nA. Why is there no current flow?

Baseline current drops to 0 nA after changing sample in the upper fluid cell. What does this mean?

Baseline current cannot be recovered between measurements.

The software will not allow the Custom Planner or Classic Capture tabs to run. How do I fix this?

The signal trace appears as a yellow band or upward spikes. What does this mean?

Particle diameter is not as expected. Why is this?

I've put my sample in the upper fluid cell but I can't see any blockades. What should I do?

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