When performing an Assistant-based measurement, the user will be asked to enter measurement details, one of which will be the Resolution Range:
The Resolution Range is an indication of the size range that can be observed at a single stretch. The default resolution range for each nanopore is at mid-range stretch (e.g. NP250 default range is 135-540 nm). The smallest particle can be adjusted within the nanopore size range to suit your sample. Once this has been edited, the largest particle will be calculated automatically but cannot be larger than the upper nanopore size range.
The Resolution Range ensures that the software guides the user to the optimised instrument setting for the selected range of particles. It also allows the user to measure the same size range every time regardless of instrument use or nanopore size.