Can qEV columns separate labeled extracellular vesicles?

Some downstream application require extracellular vesicle (e.g., exosome) samples to be labeled (e.g. PEG, PKH). 


The qEV columns are able to separate any labeled extracellular vesicles. For example, the qEV columns can separate PEG-ylated extracellular vesicles as long as the PEG is tightly bound to the extracellular vesicles. The PEG might change the size of the extracellular vesicles slightly, depending on the PEG chains, so the extracellular vesicles might come out in slightly different fractions to non PEG-ylated exosomes. The qEV columns can also be used to separate extracellular vesicles from dyes such as DiO and other membrane and non-membrane dyes.